Rosacea Meibomian Gland Dysfunction Posterior Blepharitis May Be a Marker for Earlier Associated Dyslipidaemia and Inflammation Detection and Treatment with Statins

نویسندگان

چکیده

Posterior blepharitis and dry eye are common disorders with meibomian gland dysfunction (MGD), a principal driver of their pathophysiology. Meibomian is increasingly prevalent in older populations contributory hormonal imbalances. The abnormal meibum MGD has been documented to have an excess cholesterol resultant disruption the lipid layer tear film. This leads film instability due inadequate trapping aqueous portion evaporative eye. Significant morbidity may follow ocular surface inflammation disrupting both social work function. Rosacea chronic inflammatory condition central face but can systemic associations. It especially North European onset at any age, commonly presents between thirty fifty years age. In rosacea, recognised manifestation as dyslipidaemia. Ocular rosacea predate cutaneous disease. As yet, there no directly reported evidence efficacy early identification treatment associated dyslipidaemia inflammation. We posit that sufferers be marker for dysregulated synthesis inflammation, statins maybe potential therapy. article introduces strategies utilise possible ophthalmologists, cardiologists, primary healthcare physicians treat rosacea-associated could aid overall cardiovascular mortality control sufferers, potentially earlier while also addressing de-stabilisation through lowering reduction.

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ژورنال

عنوان ژورنال: Metabolites

سال: 2023

ISSN: ['2218-1989']

DOI: https://doi.org/10.3390/metabo13070811